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J. Nyboer Electrical Impedance Plethysmography, Springﬁeld, IL: Charles C. Thomas, 1970. 15. A. K. Barros N. Ohnishi MSE behavior of biomedical eventrelated ﬁlters, IEEE Trans. Biomed. , 44: 848–855, 1997. 16. D. W. Kim C. G. Song M. H. Lee, A new ensemble averaging technique in impedance cardiography for estimation of stroke volume during treadmill exercise, Frontiers Med. Biol. , 4: 171–178, 1992. 17. E. Raaijmakers, et al. he inﬂuence of extracellular lung water on cadiac output measurements using thoracic impedance cardiography, Physiol.
The areas in which engineering blends with medicine are abundant and diverse. Biomedical engineers design imaging and diagnostic instrumentation, drug delivery systems, medical sensors, prostheses, rehabilitative devices, and artificial organs. They develop biocompatible materials, model physioJ. ), Wiley Encyclopedia of Electrical and Electronics Engineering. Copyright # 1999 John Wiley & Sons, Inc. 404 BIOMEDICAL ENGINEERING logical systems, or create patient information databases that assist in making clinical decisions.
This contact makes it essential that these materials are physiologically acceptable and pharmacologically inert, that is, nontoxic and noncarcinogenic. Additional requirements include (1) adequate mechanical strength, (2) adequate fatigue life, (3) proper weight and density, and (4) usable in reproducible and cost effective large-scale fabrication (4). Examples of biomaterials range from replacement parts to sutures, diagnostic aids, and tooth fillings. The three main classes of biomaterials are metals, ceramics, and polymers.